Articles
Lipigon and Leaderna Collaboration on Lipisense® Shows Good Progress
2024-05-15
In June 2023, Lipigon Pharmaceuticals and Leaderna Therapeutics embarked on a strategic partnership to develop and commercialize Lipigon’s drug candidate Lipisense®, aimed at treating dyslipidemias such as severe hypertriglyceridemia (SHTG). This collaboration leverages the strengths of both companies to efficiently advance the clinical progress of Lipisense®. Recently, Leaderna received approval to start a Phase I study in China.
"What is Genetic Validation?"
2023-12-18
Lipigon's Clinical Scientist Fredrik Landfors' research provides strong scientific support for targeting drugs towards ANGTPL4, the target protein for Lipigon's drug candidate Lipisense®. Central to the work is genetic validation.
Lipisense® Effectively Reduces Blood Levels of Cholesterol and Triglycerides in Animal Models
2023-09-06
An equivalent of Lipisense® for mice effectively reduces cholesterol and triglyceride levels in the blood. This has been demonstrated in a study using the atherosclerosis disease model.
Triglycerides – the Unknown Blood Fats
2022-09-30
Most people are aware that high cholesterol levels are not good and increase the risk of cardiovascular disease. However, not as many people are familiar with the other type of "dangerous" blood fats – triglycerides – which also need to be monitored and maintained within certain limits for health reasons. Gunilla Olivencrona, Prof.em. at Umeå University, co-founder of Lipigon, board member, and senior consultant, explains why.
How Does the Target Protein in Lipisense® Work?
2021-05-27
Prof. Sander Kersten, scientific advisor to Lipigon, is one of Europe's leading researchers in molecular metabolism, investigating the role of specific proteins in the body's lipid metabolism. In this interview, he discusses the target protein ANGPTL4 in the antisense drug Lipisense®, which is being developed to treat elevated blood lipids.
What are Lipids?
2021-03-16
Lipids, commonly known as fats, have vital functions in the body, but in the wrong quantity and in the wrong place, they can cause serious diseases. Gunilla Olivencrona shares further details in this article.